New shot may slash infection risk after broken bones
NCT ID NCT04964947
First seen May 18, 2026 · Last updated Jun 13, 2026 · Updated 4 times
Summary
This study tests whether giving a local antibiotic (tobramycin) directly into the wound during open fracture surgery, along with standard IV antibiotics, can lower the chance of infection. About 600 adults with open arm or leg fractures will take part. The goal is to see if this extra step reduces infections one year after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
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