New drug aims to stop dangerous gut infection from returning
NCT ID NCT05330182
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study tests an experimental drug called LMN-201 to see if it can prevent C. difficile infection from coming back after standard antibiotic treatment. About 375 adults with a recent C. diff infection will receive either LMN-201 or a placebo. The main goal is to see if more people stay infection-free with LMN-201.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baptist Health Research
Lexington, Kentucky, 40503, United States
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Clinical Alliance for Infectious Diseases - Infectious Diseases, LLC
Annandale, Virginia, 22003, United States
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Gastroenterology Center of Connecticut
Hamden, Connecticut, 06518, United States
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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IMA Clinical Research
Mount Airy, North Carolina, 27030, United States
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Kaiser Permanente
Escondido, California, 90027, United States
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Kaiser Permanente-Mid Atlantic
Springfield, Virginia, 22015, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Mayo Clinic - Rochester
Rochester, Minnesota, 55905, United States
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Metro Infectious Disease Consultants, LLC
Burr Ridge, Illinois, 60527, United States
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UW Health University Hospital
Madison, Wisconsin, 53792, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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University of South Florida
Tampa, Florida, 33606, United States
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University of Virginia School of Medicine
Charlottesville, Virginia, 22903, United States
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Weill Cornell Medicine
New York, New York, 10021, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Your dinner plate might fight c. diff: diet study aims to stop repeat infections
- FMT vs antibiotics: which works better Long-Term for c. diff?
- Hospital maps may slash infection spread
- New antibiotic CRS3123 takes on c. diff in early trial
- Gut bacteria capsules take on superbugs in antibiotic patients
- New drug combo shows promise against deadly gut infection