New kidney stone drug shows promise in early trial

NCT ID NCT06932146

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This study tested an experimental drug called LLX-424 in 51 adults who have had kidney stones before. The drug aims to lower oxalate levels in urine, which can help prevent new stones from forming. Participants took either the drug or a placebo for 8 weeks, and researchers checked for side effects and changes in urine oxalate. The trial is complete, and results will help decide if larger studies are needed.

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Contacts and locations

Locations

  • Clinical Research Site #1

    San Antonio, Texas, 78217, United States

  • Clinical Research Site #2

    Saint Paul, Minnesota, 55114, United States

  • Clinical Research Site #3

    Springfield, Missouri, 65802, United States

Conditions

Explore the condition pages connected to this study.