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Mapping pain relief: nerve blocks studied in liver donors

NCT ID NCT07252063

Knowledge-focused Sponsor: Bahçeşehir University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 30 living liver donors to see how well nerve blocks (interfascial plane blocks) control pain after surgery. Researchers mapped where the blocks worked on the skin and checked pain levels and painkiller use in the first 24 hours. The goal is to better understand these blocks to improve pain management for future donors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
interfascial plane block
What this could lead to
If successful, this could help doctors choose better nerve blocks to reduce pain after liver donation surgery.
What could go wrong
This is a small, observational study that only measures pain patterns, not a new treatment. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

Nov 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult living liver donors undergoing elective donor hepatectomy at a tertiary care center. All participants receive ultrasound-guided interfascial plane blocks as part of the institution's routine postoperative analgesia protocol. Eligible donors are aged 18 to 65 years, classified as ASA physical status I-II, and able to cooperate with postoperative cutaneous sensory mapping procedures. Individuals with contraindications to regional anesthesia, conditions preventing accurate sensory assessment, or those who decline participation are excluded.

Ages

18 to 65 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult living liver donors undergoing elective donor hepatectomy * Age 18 to 65 years * ASA physical status I-II * Patients who have received ultrasound-guided interfascial plane blocks as part of their postoperative analgesia * Ability to cooperate with postoperative sensory mapping procedures * Patients who agree to participate and provide written informed consent Exclusion Criteria: * Patients who refuse to participate or do not provide written informed consent * Patients who have not received any ultrasound-guided interfascial plane block * ASA physical status \> II * Presence of surgical incisions or wound complications preventing reliable sensory mapping * Prior major abdominal surgery that may alter cutaneous innervation patterns * Cognitive impairment limiting the ability to cooperate with sensory testing * Known psychiatric disorders (e.g., major depression, mania, schizophrenia) that may interfere with postoperative assessment * Local infection, skin disease, or dermatologic condition preventing accurate cutaneous mapping * Allergy or contraindication to local anesthetics used in the block

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain

Contacts and locations

Locations

  • Bahcesehir Unişversity Medicalpark Goztepe hospital

    Istanbul, Turkey (Türkiye)

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