New combo targets liver tumors in hard-to-treat colorectal cancer

NCT ID NCT06607458

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving a strong chemotherapy directly to the liver, followed by standard cancer pills and an injection, works better than the standard treatment alone. It is for people whose colorectal cancer has spread mostly to the liver and is no longer responding to other treatments. About 90 participants will receive either the liver-directed therapy plus standard drugs or just the standard drugs, and researchers will track how long the liver tumors stay under control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Clinical Hospital Center "Bezanijska Kosa"

    RECRUITING

    Belgrade, 11080, Serbia

  • Czech Republic - University Hospital

    RECRUITING

    Prague, Czechia

  • Helios Park-Klinikum Leipzig

    RECRUITING

    Leipzig, Germany

  • Hospital Clinic Barcelona

    RECRUITING

    Barcelona, Spain

  • Huntsman Cancer Institute, University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Instiuto Europeo de Oncologia

    RECRUITING

    Milan, Italy

  • Izmir Ekonomi

    RECRUITING

    Izmir, Turkey (Türkiye)

  • Leiden University Medical Center (LUMC)

    RECRUITING

    Leiden, Netherlands

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, Germany

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

  • Ochsner Clinic Foundation

    RECRUITING

    New Orleans, Louisiana, 70121, United States

  • The University of Kansas Clinical Research Center

    RECRUITING

    Fairway, Kansas, 66205, United States

  • UCLA Hematology/Oncology-Santa Monica

    RECRUITING

    Santa Monica, California, 90404, United States

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