New drug aims to cleanse liver in bile duct disease

NCT ID NCT05835505

First seen Nov 06, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests whether the drug BRS201 (hydroxocobalamin) can improve liver health in people with primary sclerosing cholangitis (PSC), a chronic bile duct disease. About 28 adults with PSC will take the drug or a placebo for 4 weeks each, in random order. The main goal is to see if BRS201 lowers a key liver enzyme (ALP) linked to disease activity.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Chestnut Hill, Massachusetts, 02467, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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