New drug combo aims to stop liver cancer recurrence before surgery

NCT ID NCT07515469

First seen Apr 08, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests whether giving a combination of two immunotherapy drugs (iparomlimab and tuvonralimab) before surgery can help prevent liver cancer from returning in people with early-stage disease at high risk of recurrence. About 30 adults aged 18-75 with resectable stage IB or IIA hepatocellular carcinoma will receive the treatment before their scheduled surgery. The main goal is to see how many patients remain cancer-free one year after surgery.

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