Can a mushroom boost your brain? Lion's mane put to the test

NCT ID NCT07759687

Not yet recruiting Symptom relief Sponsor: Northumbria University Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates whether different doses of Lion's mane mushroom extract can improve attention and mood in healthy adults aged 18 to 45. Participants will receive the extract and a placebo in a crossover design, allowing each person to serve as their own control. The trial measures speed and accuracy of attention through cognitive tasks, aiming to identify the optimal acute dose for potential cognitive benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lion's Mane fruiting bodies extract (20:1 ratio)
What this could lead to: If effective, Lion's mane could offer a natural, non-prescription option to sharpen attention and lift mood in healthy people.
What could go wrong: This is a small, early-stage study with only 24 participants, so results may not apply broadly. The extract's effects on attention and mood are not yet proven, and optimal dosing remains unknown.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTENTION

Contacts and locations

Locations

Brain, Performance and Nutrition Research Centre

Newcastle upon Tyne, Tyne and Wear, NE1 8ST, United Kingdom

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