Can a drug nip myeloma in the bud? new trial aims to stop cancer before it starts
NCT ID NCT06140524
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times
Summary
This Phase 2 trial is testing an investigational drug called linvoseltamab in 116 people with precancerous blood conditions that raise their risk of developing multiple myeloma. The goal is to see if the drug can eliminate abnormal plasma cells and lab signs of disease. Researchers will also monitor side effects and how the drug behaves in the body.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AZ Sint Maarten Algemeen Ziekenhuis Emmaus
RECRUITINGMechelen, Flanders, 2800, Belgium
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AZ St.-Elisabeth Herentals vzw
RECRUITINGHerentals, Antwerp, 2200, Belgium
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Algemeen Ziekenhuis (AZ) Klina
RECRUITINGBrasschaat, Antwerpen, 2930, Belgium
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Algemeen Ziekenhuis AZ Delta
RECRUITINGRoeselare, West-Vlaanderen, 8800, Belgium
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Algemeen Ziekenhuis St Jan Brugge Oostende Av
RECRUITINGBruges, West-Vlaanderen, 8000, Belgium
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Azienda Ospedaliero Universitaria (AOU) SS. Antonio e Biagio e Cesare Arrigo
RECRUITINGAlessandria, 15121, Italy
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Centre Hospitalier Universitaire De Poitiers
RECRUITINGPoitiers, New Aquitaine, 86000, France
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Cork University Hospital
RECRUITINGCork, T12 EC8P, Ireland
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Galway University Hospital
RECRUITINGGalway, Connacht, H91 YR71, Ireland
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Hospital Clinico Universitario Virgen De La Arrixaca
RECRUITINGEl Palmar, Murcia, 30120, Spain
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Hospital General Universitario Morales Meseguer
RECRUITINGMurcia, 30008, Spain
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Hospital Sant Pau
RECRUITINGBarcelona, 08041, Spain
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Hospital Universitari Mutua Terrassa
RECRUITINGTerrassa, Barcelona, 08221, Spain
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Hospital Universitario Virgen de las Nieves
RECRUITINGGranada, Andalusia, 18014, Spain
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Hospital de Cabuenes
RECRUITINGGijón, Principality of Asturias, 33203, Spain
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IRCCS Ospedale Policlinico San Martino
RECRUITINGGenoa, Genova, 16132, Italy
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Institut Catala dOncologia (ICO Hospitalet)
RECRUITINGBarcelona, 08908, Spain
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Institut Curie
RECRUITINGParis, Île-de-France Region, 75005, France
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Istituto Romagnolo per lo Studio Dei Tumori Dino Amadori
RECRUITINGMeldola, Forli-Cesena, 47014, Italy
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Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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Mater Misericordiae University Hospital
RECRUITINGDublin, D07 R2WY, Ireland
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NYU Langone Health Perlmutter Cancer Center
RECRUITINGNew York, New York, 10016, United States
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Ospedale Santa Maria delle Croci
RECRUITINGRavenna, 48121, Italy
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Pratia MCM Krakow
RECRUITINGKrakow, Malopolska, 30-510, Poland
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San Paolo Hospital
RECRUITINGMilan, Lombardy, 20142, Italy
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Specjalistyczny Szpital im A. Sokolowskiego w Walbrzychu
RECRUITINGWałbrzych, Lower Silesian Voivodeship, 58-309, Poland
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Stony Brook University Hospital
RECRUITINGStony Brook, New York, 11794, United States
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Swietokrzyskie Centrum Onkologii
RECRUITINGKielce, Świętokrzyskie Voivodeship, 25-734, Poland
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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UOC Ematologia e Terapia Cellulare - PO Mazzoni AST Ascoli Piceno
RECRUITINGAscoli Piceno, 63100, Italy
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Universita degli Studi di Pavia - Fondazione IRCCS Policlini
RECRUITINGPavia, 27100, Italy
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Universitaru Hospital La Princesa
RECRUITINGMadrid, 28006, Spain
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University Clinical Center / Medical University of Gdansk
RECRUITINGGdansk, Pomeranian Voivodeship, 80-219, Poland
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University of Michigan Health
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Washington
RECRUITINGSeattle, Washington, 98109, United States
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Wojewodzki Szpital Zespolony - Ludwik Rydygier Provincial Hospital
RECRUITINGTorun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
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Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. Mikolaja Kopernika w Lodzi (Copernicus Memorial Hospital)
RECRUITINGLodz, 93-513, Poland
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Ziekenhuis Netwerk Antwerpen Cadix, Hematology
RECRUITINGAntwerp, 2030, Belgium
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
linvoseltamab (a drug given by injection)
What this could lead to
If it works, this could point toward a way to stop precancerous conditions from turning into multiple myeloma, potentially preventing the disease.
What could go wrong
This is an early Phase 2 study with only 116 participants, so results may not apply to everyone. The drug may cause side effects, and it is not yet proven to prevent cancer.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.