New hope for older AML patients: targeted radiation combo enters human testing
NCT ID NCT06802523
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new three-drug combination for adults with newly diagnosed acute myeloid leukemia (AML) who cannot receive standard chemotherapy. The treatment includes a targeted radiation antibody (lintuzumab-Ac-225) plus two oral drugs (venetoclax and ASTX-727). The goal is to find a safe dose and see if the combination helps more patients achieve remission. About 53 people will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yale University Cancer Center LAO
New Haven, Connecticut, 06520, United States
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