New hope for older AML patients: targeted radiation combo enters human testing
NCT ID NCT06802523
First seen Jan 07, 2026 · Last updated Jun 16, 2026 · Updated 26 times
Summary
This early-phase study tests a new three-drug combination for adults with newly diagnosed acute myeloid leukemia (AML) who cannot receive standard chemotherapy. The treatment includes a targeted radiation antibody (lintuzumab-Ac-225) plus two oral drugs (venetoclax and ASTX-727). The goal is to find a safe dose and see if the combination helps more patients achieve remission. About 53 people will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Yale University Cancer Center LAO
New Haven, Connecticut, 06520, United States
Conditions
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