New hope for rare blood disorder: linprixel trial launches

NCT ID NCT07149818

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2 trial tests linprixel, a daily pill, in 22 adults with relapsed or refractory autoimmune hemolytic anemia (AIHA). The study aims to see if the drug can improve red blood cell counts after 12 weeks. Participants start at 40mg daily, with possible dose increases if needed. The trial is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

linprixel (parsaclisib)

What this could lead to

If successful, this could offer a new treatment option for people with hard-to-treat autoimmune hemolytic anemia, potentially reducing the need for long-term steroids.

What could go wrong

This is a small, early-phase trial with only 22 participants and no comparison group. The drug may not work for everyone, and side effects are possible. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune hemolytic anemia autoimmune hemolytic anemia, warm type cold agglutinin disease Evans syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.