New combo therapy aims to beat staph blood infections
NCT ID NCT06958835
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 36 times
Summary
This study tests whether adding the antibiotic linezolid to standard treatment improves outcomes for people with Staphylococcus aureus bloodstream infections. About 606 hospitalized adults will receive either linezolid or a placebo for five days. The goal is to see if the combination reduces complications, helps patients return to normal function, and improves survival.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre hospitalier universitaire vaudois (CHUV)
NOT_YET_RECRUITINGLausanne, Canton of Vaud, Switzerland
Contact
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Ente Ospedaliero Cantonale (EOC)
RECRUITINGLugano, Canton Ticino, Switzerland
Contact
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HOCH Health Ostschweiz, Kantonsspital St.Gallen
NOT_YET_RECRUITINGSankt Gallen, Switzerland
Contact
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Hôpital du Jura
NOT_YET_RECRUITINGDelémont, Canton of Jura, Switzerland
Contact
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Hôpitaux universitaires de Genève (HUG)
NOT_YET_RECRUITINGGeneva, Canton of Geneva, Switzerland
Contact
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Inselspital Bern
NOT_YET_RECRUITINGBern, Switzerland
Contact
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Kantonsspital Aarau (KSA)
RECRUITINGAarau, Canton of Aargau, Switzerland
Contact
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Kantonsspital Winterthur (KSW)
NOT_YET_RECRUITINGWinterthur, Canton of Zurich, Switzerland
Contact
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St. Claraspital
RECRUITINGBasel, Canton of Basel-City, Switzerland
Contact
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Stadtspital Zürich Triemli
RECRUITINGZurich, Switzerland
Contact
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University Hospital Basel (USB)
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Universitätsspital Zürich (USZ)
RECRUITINGZurich, Switzerland
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
linezolid
What this could lead to
If it works, this could lead to a better treatment strategy for serious staph bloodstream infections, reducing complications and improving survival.
What could go wrong
This is a mid-stage trial, so results may not confirm benefit. Adding linezolid also carries risks like side effects or drug interactions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.