New combo targets tricky lung cancer transformation after TKI failure

NCT ID NCT07001995

First seen Mar 26, 2026 · Last updated Apr 30, 2026 · Updated 4 times

Summary

This study tests a combination of limertinib plus chemotherapy (carboplatin and etoposide) in 30 adults with a specific type of lung cancer (EGFR-mutant NSCLC) that has transformed into small cell lung cancer after initial targeted therapy stopped working. The goal is to see if this new treatment can control the cancer longer. Participants must have had prior EGFR-TKI treatment and biopsy-confirmed transformation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-SMALL CELL LUNG CANCER (NSCLC) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yongchang Zhang

    Changsha, Hunan, 410013, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.