Can morning light boost melanoma treatment? new trial tests simple iPad therapy

NCT ID NCT07628894

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests whether a home-based morning light therapy program can help people with advanced melanoma who are receiving tumor-infiltrating lymphocyte (TIL) therapy. The light therapy is delivered through an iPad app and aims to improve the body's natural sleep-wake cycle, which may be disrupted by cancer and hospital stays. The study will enroll 8 participants and focus on whether the light therapy is safe and easy to follow.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Circadian-Optimized Light Therapy (COLT) via iPad app
What this could lead to
If it works, this could point toward a simple way to boost the effectiveness of TIL therapy for advanced melanoma by improving patients' sleep-wake cycles.
What could go wrong
This is a very early, small pilot study with only 8 participants. It is designed mainly to test if the light therapy is safe and doable, not whether it actually helps. The results may not apply to other patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

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