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Could a quieter, dimmer ICU protect Patients' brains?

NCT ID NCT06294158

Knowledge-focused Sponsor: Medical University of Graz Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

Delirium is a common and serious problem for critically ill patients in intensive care units. Researchers at the Medical University of Graz are measuring light and noise levels in three ICUs to see whether these environmental factors are associated with the development of delirium. They will enroll about 250 to 300 adult patients who are expected to stay in the ICU for at least two more days, and they will assess each patient daily for delirium using a standard bedside test. The goal is to learn whether adjusting ICU lighting and sound could become a way to reduce delirium risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If light and noise levels are linked to delirium, hospitals could adjust ICU lighting and sound to help protect patients' thinking and memory during critical illness.
What could go wrong
This is an observational pilot study, so it can show associations but not prove that light or noise causes delirium. Many other factors affect delirium risk, and the findings may not apply to other hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

315 people

The number who actually took part.

Started

Oct 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients shall be included into the study if they can be expected to remain in the ICU for at least another two days, if they are not yet in delirium, if the ICU environment is not actively modified for therapeutic reasons (e.g., in the treatment of burns patients), if no treatment limitations are in place and if the patient can provide written informed consent. In those patients, who cannot provide informed consent upon recruitment due to their current illness or injury, consent by patients or their representatives shall be sought if and once they regain capacity (deferred consent).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Adult patients (age ≥ 18 years) * Admission to participating Intensive Care Unit * Expected (further) stay in participating Intensive Care Unit ≥ 48 hours * Not (currently) deeply sedated (RASS ≥ -3) Exclusion Criteria * Patient already in delirium (CAM-ICU positive) * Environmental modification due to treatment necessities (e.g., burns care) * Advanced directives / Treatment limitation * Current inclusion in other (interventional) trial * Documented patient refusal in advance

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Conditions

The condition(s) this trial relates to.

Critical Illness delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical illness Delirium

Contacts and locations

Locations

  • University Medical Centre Graz, Dept. of Anaesthesiology and Intensive Care Medicine

    Graz, Styria, 8036, Austria

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