Could a drug combo ease ME/CFS and long COVID? new trial launches
NCT ID NCT06366724
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 32 times
Summary
This study tests whether two medications—Pyridostigmine and Low-Dose Naltrexone—can improve daily functioning in people with ME/CFS or Long COVID who also have orthostatic intolerance (trouble standing). 160 adults aged 18-70 will be randomly assigned to take one or both drugs or placebos for about 3 months. The goal is to see if these treatments help with energy, activity, and overall well-being.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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