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Lifestyle overhaul may cut dementia risk in latin america

NCT ID NCT06492967

Completed Prevention Sponsor: Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a structured lifestyle program—including diet, exercise, and cognitive training—can help prevent cognitive decline in older adults at risk for dementia. Over 1,000 participants aged 60-77 from 12 Latin American countries took part. The goal was to see if such a program is feasible and could eventually reduce dementia rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lifestyle intervention (diet, exercise, cognitive training, and cardiometabolic risk management)
What this could lead to
If successful, this could show that lifestyle changes can prevent or delay dementia in high-risk older adults, influencing public health policies.
What could go wrong
This is a feasibility study, not a large-scale trial. It measures recruitment and adherence, not whether the intervention actually prevents dementia. Results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease brain disorder dementia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE

Contacts and locations

Locations

  • Antioquia University

    Antioquia, Colombia

  • Centro Neurológico Mente Activa

    La Paz, Bolivia

  • Clínica de la Memoria - Hospital Británico

    Montevideo, Uruguay

  • Fleni

    Ciudad Autonoma de Buenos Aire, Argentina

  • Hospital Clínica Bíblica

    San José, Costa Rica

  • Hospital Clínico Universidad de Chile

    Santiago, Chile

  • Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez

    Mexico City, Mexico

  • Instituto Peruano de Neurociencas

    Lima, Peru

  • Neuromedicenter - Cognitive Disorders Unit

    Quito, Ecuador

  • Universidad Nacional Pedro Henriquez Urena (UNPHU)

    Santo Domingo, Dominican Republic

  • Universidad de Puerto Rico

    San Juan, Puerto Rico

  • Universidade Federal de Minas Gerais

    Belo Horizonte, Minas Gerais, Brazil

  • University of Sao Paulo School of Medicine

    São Paulo, Brazil

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