Could a common numbing drug cut opioid needs in sickle cell crises?
NCT ID NCT07274254
First seen Jan 07, 2026 · Last updated Apr 28, 2026 · Updated 21 times
Summary
This study tests whether adding lidocaine to standard pain treatment can lower the amount of opioids needed by adults with sickle cell disease during a severe pain crisis. About 104 participants will be randomly assigned to receive either lidocaine or a placebo alongside usual care. The main goal is to see if lidocaine helps reduce total opioid use while in the intensive care unit.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHRU Tours - Hôpital Bretonneau
Tours, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Bordeaux
Bordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Guadeloupe
Les Abymes, Guadeloupe
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU La Timone
Marseille, France
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CHU Lille
Lille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Orléans
Orléans, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Poitiers
Poitiers, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Rouen
Rouen, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Nantes
Nantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Tenon APHP
Paris, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oncopole Toulouse
Toulouse, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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