Could a common numbing drug cut opioid needs in sickle cell emergencies?

NCT ID NCT07274254

First seen Jan 07, 2026 · Last updated Jun 16, 2026 · Updated 28 times

Summary

This study tests whether adding lidocaine, a numbing medicine, to standard pain treatment can lower the amount of strong opioids needed during severe sickle cell pain crises. About 104 adults with sickle cell disease who are in the intensive care unit for a pain crisis will take part. The goal is to see if lidocaine helps control pain while reducing opioid use and side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU Tours - Hôpital Bretonneau

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Bordeaux

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Guadeloupe

    Les Abymes, Guadeloupe

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU La Timone

    Marseille, France

  • CHU Lille

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Orléans

    Orléans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Poitiers

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Rouen

    Rouen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Nantes

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Tenon APHP

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oncopole Toulouse

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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