Can a lidocaine shot ease biopsy pain? new study says maybe.

NCT ID NCT06546254

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a lidocaine injection into the cervix (paracervical block) reduces pain during endometrial biopsy. 96 women were randomly assigned to receive either lidocaine or a gentle tap with a capped needle (control). The main goal was to see if pain scores were lower with lidocaine. Results could help make this common procedure less painful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lidocaine
What this could lead to
If it works, this could offer a simple way to reduce pain during endometrial biopsy, making the procedure more tolerable.
What could go wrong
This is a small, completed trial with only 96 participants. The control group received a tapping sensation, not a placebo injection, so results may not be widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OPG

    Toronto, Ontario, M5G 1Z5, Canada

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