Can a lidocaine shot ease biopsy pain? new study says maybe.
NCT ID NCT06546254
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a lidocaine injection into the cervix (paracervical block) reduces pain during endometrial biopsy. 96 women were randomly assigned to receive either lidocaine or a gentle tap with a capped needle (control). The main goal was to see if pain scores were lower with lidocaine. Results could help make this common procedure less painful.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine
What this could lead to
If it works, this could offer a simple way to reduce pain during endometrial biopsy, making the procedure more tolerable.
What could go wrong
This is a small, completed trial with only 96 participants. The control group received a tapping sensation, not a placebo injection, so results may not be widely applicable.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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OPG
Toronto, Ontario, M5G 1Z5, Canada