Targeted drug duo tested for tough blood cancers

NCT ID NCT04874194

Summary

This study tested a combination of two drugs, omacetaxine and venetoclax, for adults with acute myeloid leukemia or myelodysplastic syndrome that has returned or stopped responding to treatment, and who have a specific genetic change called RUNX1. The goal was to find the safest, most effective dose and see if the combination could help control these aggressive blood cancers. The trial was terminated early and enrolled 24 participants.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.