New drug duo aims to tame aggressive blood cancers

NCT ID NCT04874194

Summary

This study tested whether combining two drugs, omacetaxine and venetoclax, could help control acute myeloid leukemia or myelodysplastic syndrome that had returned or stopped responding to other treatments in patients with a specific genetic change called RUNX1. The goal was to find the safest, most effective dose and see if the combination could reduce or eliminate cancer cells. The trial was terminated early and enrolled 24 adult participants.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.