Could a breast cancer drug improve abortion care?

NCT ID NCT07767435

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This study tests whether adding letrozole, a drug commonly used for breast cancer, to the standard medication misoprostol can improve the complete termination of second-trimester pregnancies (14-20 weeks). The trial will compare the combination against misoprostol alone in 80 women with a failed pregnancy. The main goal is to see if the combination leads to a higher rate of complete abortion, potentially making the process safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
letrozole combined with misoprostol
What this could lead to
If adding letrozole works, it could make second-trimester abortion procedures faster and more complete, reducing the need for additional surgical intervention.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not be conclusive. Adding letrozole could also increase side effects without improving outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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