Experimental drug leronlimab tested in 484 severe COVID-19 patients

NCT ID NCT04347239

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called leronlimab in 484 hospitalized adults with severe or critical COVID-19. Participants received weekly injections of the drug or a placebo to see if it could lower the risk of death and improve recovery. The trial is now complete, and results help understand whether this treatment can control severe disease.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Cardiovascular, LLC

    Alexander City, Alabama, 35010, United States

  • Atlantic Health System Hospital

    Morristown, New Jersey, 07962-1905, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Baylor Scott & White Research Institute

    Dallas, Texas, 75204, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Center for Advanced Research & Education (CARE)

    Gainesville, Georgia, 30501, United States

  • Good Samaritan Hospital Corvallis

    Corvallis, Oregon, 97330, United States

  • Holy Name Medical Center

    Teaneck, New Jersey, 07666, United States

  • James A. Haley Veterans' Hospital

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • New York Community Hospital of Brooklyn

    Brooklyn, New York, 11229, United States

  • Novant Health

    Winston-Salem, North Carolina, 27103, United States

  • Ohio Health

    Columbus, Ohio, 43215, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • St. Barnabas

    Livingston, New Jersey, 07052, United States

  • St. Jude Medical Center

    Fullerton, California, 92835, United States

  • UCLA

    Los Angeles, California, 90095, United States

  • University of Texas

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.