Can a pill help Night-Shift workers sleep during the day?

NCT ID NCT06231641

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether lemborexant, a sleep medication, can help people who work night shifts get better daytime sleep without feeling drowsy later. Five healthy adults who had not done shift work in the past year took either lemborexant or a placebo before daytime sleep in a lab. The goal was to see if the drug improves total sleep time and reduces wakefulness after falling asleep.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lemborexant (Dayvigo)

What this could lead to

If it works, this could point toward a treatment for shift work disorder, helping people sleep better after night shifts.

What could go wrong

This is a very small, early feasibility study with only 5 participants, and it was terminated. Results may not apply to everyone, and lemborexant may cause next-day drowsiness or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder circadian rhythm sleep disorder, shift work type

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CIUSSS du Nord de l'ile de Montreal (CIUSSS-NIM) - Hôpital du Sacré-Cœur de Montréal (HSCM)

    Montreal, Quebec, H4J 1C5, Canada