New drug cocktail aims to shrink Hard-to-Treat tumors

NCT ID NCT07331155

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called LBL-024 combined with standard chemotherapy and immunotherapy for people with advanced solid tumors. About 110 adults with good overall health will receive the treatment to see if tumors shrink or stop growing. The goal is to find a safer and more effective option for those who have limited choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LBL-024 (an experimental drug) combined with chemotherapy drugs (cisplatin, paclitaxel, 5-fluorouracil, capecitabine) and tislelizumab (an immunotherapy)

What this could lead to

If successful, this could point toward a new treatment option for people with advanced solid tumors that are hard to treat.

What could go wrong

This is an early Phase 2 trial with only 110 participants, so results may not apply to everyone. The combination therapy may cause side effects or not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AnYang Tumor Hospital

    NOT_YET_RECRUITING

    Anyang, Henan, 455000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong Cancer Hospital

    RECRUITING

    Jinan, Shandong, 250117, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Suining Central Hospital

    RECRUITING

    Suining, Sichuan, 629099, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Henan University of Science & Technology

    RECRUITING

    Luoyang, Henan, 471003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 451191, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••