Pacemaker tweak may boost heart function in failure patients

NCT ID NCT06436053

Recruiting now Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests a special pacemaker setting called SyncAV, used with left bundle branch area pacing, in people with heart failure and a heart block. The goal is to see if this setting can improve the heart's electrical timing and pumping strength. About 50 adults who already need a pacemaker will take part, and researchers will measure changes in heart function during the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left bundle branch area pacing with SyncAV feature
What this could lead to: If successful, this could improve heart pumping efficiency and reduce symptoms for people with heart failure who need a pacemaker.
What could go wrong: This is a small, early-stage study looking at short-term effects only. Long-term benefits or risks are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

I.R.C.C.S. Policlinico San Donato
RECRUITING

San Donato Milanese, MI, 20097, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

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