New lung cancer pill shows promise in Head-to-Head trial
NCT ID NCT04248829
First seen May 29, 2026 · Last updated Jun 11, 2026 · Updated 3 times
Summary
This study tested a new drug called lazertinib against an older drug, gefitinib, in 393 people with advanced non-small cell lung cancer that has specific EGFR mutations. Participants took one of the two pills daily as their first treatment. The main goal was to see how long the cancer stayed under control. Results help doctors choose better first-line therapy for this type of lung cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Adana Baskent Practice and Research Hospital
Adana, 1120, Turkey (Türkiye)
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Ajou University Hospital
Suwon, Gyeonggi-do, 16499, South Korea
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Ankara Liv Hospital
Ankara, 06680, Turkey (Türkiye)
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Arkhangelsk Regional Clinical Oncological Dispensary
Arkhangelsk, Arkhangelskaya oblast, 163045, Russia
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Asan Medical Center
Seoul, 05505, South Korea
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Attikon Hospital
Athens, 12462, Greece
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Budgetary Healthcare Institution of Omsk Region "Clinical Oncology Dispensary"
Omsk, 644013, Russia
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CHA Bundang Medical Center, CHA University
Seongnam-si, Gyeonggi-do, 13496, South Korea
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Chiang Mai University - Faculty of Medicine
Chiang Mai, 50200, Thailand
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Chungbuk National University Hospital
Cheongju-si, North Chungcheong, 28644, South Korea
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Clinical Center Kragujevac
Kragujevac, 34000, Serbia
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Clinical Hospital Center "Bezanijska Kosa"
Belgrade, Belgrade, 11080, Serbia
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Cukurova University Medical Faculty
Adana, 1330, Turkey (Türkiye)
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Debreceni Egyetem
Debrecen, H-4012, Hungary
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Eugenideio Therapeutirio - Ongcology Department
Athens, 11528, Greece
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First St. Petersburg State Medical University n. a. Pavlov
Saint Petersburg, 197022, Russia
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GAUZ Republican clinical oncology dispensary of the Ministry
Kazan', 420029, Russia
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GBUZ "Regional clinical oncologic dispensary of Volgograd"
Volgograd, 400138, Russia
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GBUZ of Nizhny Novgorod region Clinical diagnostic center
Nizhny Novgorod, Nizhny Novgorod Oblast, 603006, Russia
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Gachon University Gil Medical Center
Incheon, 21565, South Korea
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Gyeongsang National University Hospital
Jinju, Gyeongsangnam-do, 52727, South Korea
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Hacettepe University Medical Faculty - Medical Oncology
Ankara, 6230, Turkey (Türkiye)
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Hospital Pulau Pinang
George Town, Pulau Pinang, 10400, Malaysia
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Hospital Raja Perempuan Zainab Ii
Kota Bharu, Kelantan, 15586, Malaysia
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Hospital Sultan Ismail
Johor Bahru, Johor, 81100, Malaysia
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Hospital Tengku Ampuan Afzan
Kuantan, Pahang, 25100, Malaysia
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Hospital Umum Sarawak
Kuching, Sarawak, 10450, Malaysia
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Inje University Haeundae Paik Hospital
Busan, 48108, South Korea
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Inonu University Turgut Ozal Medical Center
Malatya, 44280, Turkey (Türkiye)
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Institute for Pulmonary Diseases of Vojvodina
Kamenitz, Vojvodina, 21204, Serbia
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Istanbul Medeniyet University Goztepe Training and Research Hospital - Medical Oncology
Istanbul, 34722, Turkey (Türkiye)
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Kangbuk Samsung Hospital
Seoul, 03181, South Korea
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Keimyung University Dongsan Medical Center
Daegu, 42601, South Korea
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Kocaeli University Medical Faculty
Kocaeli, 41380, Turkey (Türkiye)
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Komunalne nekomertsiine pidpryiemstvo "Miska klinichna likarnia №4" Dniprvskoi miskoi rady", khimioterapevtychne viddilennia z dennym statsionarom, Derzhavnyi zaklad "Dnipropetrovskyi derzhavnyi medychnyi universitet", kafedra onkolohii i medychnoi radio
Dnipro, 49102, Ukraine
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Komunalne nekomertsiine pidpryiemstvo Kharkivskoi oblasnoi rady "Oblasnyi klinichnyi spetsializovanyi dyspanser radiatsiinoho zakhystu naselennia" - khirurhichne viddilennia
Kharkiv, Kharkiv Oblast, 61166, Ukraine
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Komunalne nekomertsiine pidpryiemstvo Sumskoi oblasnoi rady "Sumskyi klinichnyi onkolohichnyi tsentr", onkotorakalne viddilennia, Sumskyi derzhavnyi universytet, kafedra onkolohii ta radiolohii, m. Sumy
Sumy, 40022, Ukraine
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Korea University Anam Hospital
Seoul, 02841, South Korea
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Kyiv City Clinical Oncology Center - Department of Chemotherapy
Kyiv, 3115, Ukraine
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LLC "Eurocityclinic"
Saint Petersburg, 197022, Russia
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Limited Liability Company "AV Medical Group" - Oncology
Saint Petersburg, 197082, Russia
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MBUZ City Clinical Hospital #1
Novosibirsk, Russia
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Manila Doctors Hospital - Clinical Trial Office
Manila, Quezon, 1000, Philippines
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Medical Point İzmir Hospital
Izmir, 35560, Turkey (Türkiye)
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Medincentre (GLAVUPDK)
Moscow, 119034, Russia
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Medychnyi tsentr Tovarystva z obmezhenoiu vidpovidalnistiu "Onkolaif"
Zaporizhzhia, 69059, Ukraine
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National Cancer Center
Goyang-si, Gyeonggi-do, 10408, South Korea
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National Taiwan University Hospital
Taipei, 10002, Taiwan
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National University Hospital
Singapore, 119074, Singapore
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Oblasne komunalne nekomertsiine pidpryiemstvo "Bukovynskyi klinichnyi onkolohichnyi tsentr", strukturnyi pidrozdil klinichnoi onkolohii, m.Chernivtsi
Chernivtsi, 58013, Ukraine
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Perpetual Succour Hospital
Cebu, 6000, Philippines
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Philippine General Hospital
Manila, 1000, Philippines
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Podilskyi rehionalnyi tsentr onkolohii, viddilennia khimioterapii
Vinnytsia, 21029, Ukraine
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Prince of Songkla University
Hat Yai, 90110, Thailand
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Princess Alexandra Hospital
Woolloongabba, Queensland, 4102, Australia
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Private medical institution "Euromedservice"
Pushkin, 196603, Russia
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Ramathibodi Hospital, Mahidol University
Bangkok, 10400, Thailand
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Republic Clinical Oncology Despensary
Kazan', 420029, Russia
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SMG-SNU Boramae Medical Center
Seoul, 07061, South Korea
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Saint-Petersburg City Clinical Oncology Dispensary
Saint Petersburg, 198255, Russia
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Samsung Medical Center
Seoul, 06351, South Korea
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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Severance Hospital
Seoul, 03722, South Korea
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Siriraj Hospital
Bangkok, 10700, Thailand
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Srinagarind Hospital, Khon Kaen University
Khon Kaen, 40002, Thailand
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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The Catholic University of Korea, Bucheon St. Mary's Hospital
Bucheon-si, Gyeonggi-do, 14647, South Korea
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The Catholic University of Korea, Eunpyeong St.Mary's Hospital
Seoul, 03312, South Korea
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The Catholic University of Korea, Seoul St. Mary's Hospital
Seoul, 06591, South Korea
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The Catholic University of Korea, St. Vincent's Hospital
Suwon, Gyeonggi-do, 16247, South Korea
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Theageneio Anticancer Hospital of Thessaloniki
Thessaloniki, 54007, Greece
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Trakya University Medical Faculty
Edirne, 22030, Turkey (Türkiye)
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Tsentralna miska klinichna likarnia
Uzhhorod, Zakarpattia Oblast, 88000, Ukraine
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Törökbálinti Tüdőgyógyintézet
Törökbálint, 2045, Hungary
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Ulsan University Hospital
Ulsan, 44033, South Korea
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University Malaya Medical Centre
Kuala Lumpur, Selangor, 59100, Malaysia
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VitaMed LLC
Moscow, 121309, Russia
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Yaroslavl regional oncology hospital
Yaroslavl, 150054, Russia
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Yeungnam University Medical Center
Daegu, 42415, South Korea
Conditions
Explore the condition pages connected to this study.