Race against time: new combo tested to save brains after late stroke

NCT ID NCT06221371

First seen Jan 06, 2026 · Last updated Apr 18, 2026 · Updated 20 times

Summary

This study tested whether adding a clot-busting drug (tenecteplase) before a mechanical clot removal procedure leads to better recovery for stroke patients. It involved 391 adults who had a stroke caused by a major brain artery blockage and could be treated 4.5 to 24 hours after symptoms began. The main goal was to see which approach helped more patients regain independence 90 days later.

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Contacts and locations

Locations

  • Beijing Daxing District People's Hospital

    Beijing, Beijing Municipality, China

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100070, China

  • Dalian Municipal Central Hospital

    Dalian, Liaoning, China

  • First Affiliated Hospital of Wannan Medical College

    Wuhu, Anhui, China

  • First Affiliated Hospital of Xi 'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

  • First People's Hospital of Chenzhou

    Chenzhou, Hunan, 423000, China

  • Heze Municipal Hospital

    Heze, Shandong, 274400, China

  • Jining NO.1 People's Hospital

    Jining, Shandong, China

  • Liaocheng Third People's Hospital

    Liaocheng, Shandong, 252006, China

  • Linyi Central Hospital

    Linyi, Shandong, China

  • Linyi People's Hospital

    Linyi, Shandong, 276003, China

  • People's Hospital of Queshan

    Zhumadian, Henan, China

  • Puyang Oilfield General Hospital

    Puyang, Henan, China

  • Qingdao Central Hospital

    Qingdao, Shandong, 266000, China

  • Rizhao People's Hospital

    Rizhao, Shandong, 276800, China

  • Rizhao Traditional Chinese Medicine Hospital

    Rizhao, Shandong, 276800, China

  • The 2nd affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, China

  • The First Affiliated Hospital of USTC

    Hefei, Anhui, China

  • Weifang People's Hospital

    Weifang, Shandong, China

  • Zaozhuang Municipal Hospital

    Zaozhuang, Shandong, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, China

Conditions

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