Race against time: new combo therapy tested to save brains after late strokes

NCT ID NCT06221371

Summary

This study tested whether adding an intravenous clot-busting drug (tenecteplase) before a standard surgical procedure to remove a clot is better than the surgery alone. It involved 391 adults who had a stroke caused by a blockage in a major brain artery and arrived for treatment 4.5 to 24 hours after symptoms began. The main goal was to see if the two-step approach led to better recovery and less disability 90 days later.

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Contacts and locations

Locations

  • Beijing Daxing District People's Hospital

    Beijing, Beijing Municipality, China

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100070, China

  • Dalian Municipal Central Hospital

    Dalian, Liaoning, China

  • First Affiliated Hospital of Wannan Medical College

    Wuhu, Anhui, China

  • First Affiliated Hospital of Xi 'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

  • First People's Hospital of Chenzhou

    Chenzhou, Hunan, 423000, China

  • Heze Municipal Hospital

    Heze, Shandong, 274400, China

  • Jining NO.1 People's Hospital

    Jining, Shandong, China

  • Liaocheng Third People's Hospital

    Liaocheng, Shandong, 252006, China

  • Linyi Central Hospital

    Linyi, Shandong, China

  • Linyi People's Hospital

    Linyi, Shandong, 276003, China

  • People's Hospital of Queshan

    Zhumadian, Henan, China

  • Puyang Oilfield General Hospital

    Puyang, Henan, China

  • Qingdao Central Hospital

    Qingdao, Shandong, 266000, China

  • Rizhao People's Hospital

    Rizhao, Shandong, 276800, China

  • Rizhao Traditional Chinese Medicine Hospital

    Rizhao, Shandong, 276800, China

  • The 2nd affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, China

  • The First Affiliated Hospital of USTC

    Hefei, Anhui, China

  • Weifang People's Hospital

    Weifang, Shandong, China

  • Zaozhuang Municipal Hospital

    Zaozhuang, Shandong, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, China

Conditions

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