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Laser light may help heal nerves in carpal tunnel syndrome

NCT ID NCT07714720

Disease control Sponsor: University of Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study tests whether low-level laser therapy, when added to standard physiotherapy, can improve nerve healing in people with mild-to-moderate carpal tunnel syndrome. Participants receive either real or sham laser sessions three times a week for four weeks. The researchers measure nerve function, nerve structure, and a blood marker of nerve repair to see if the laser boosts recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
photobiomodulation (low-level laser therapy) using an 830 nm laser device
What this could lead to
If effective, this could offer a non-invasive way to improve nerve healing and reduce symptoms in people with carpal tunnel syndrome.
What could go wrong
This is a small, early-stage trial with 70 participants, so results may not apply to everyone. The laser may not provide added benefit over standard physiotherapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria * Age 18-60 years * Clinical diagnosis of unilateral mild-to-moderate carpal tunnel syndrome based on positive Phalen test and/or Tinel sign * Electrophysiological confirmation of CTS via nerve conduction study (NCS) meeting AANEM 2012 diagnostic criteria for mild-to-moderate CTS * No prior photobiomodulation or laser therapy to the affected wrist within the preceding 3 months * Ability to attend 3 treatment sessions per week for 4 consecutive weeks * Able and willing to provide written informed consent (in Urdu or English) Exclusion Criteria * Bilateral carpal tunnel syndrome * Previous surgical release of the carpal tunnel on the affected side * Systemic peripheral neuropathy (e.g., diabetes mellitus, hypothyroidism, Charcot-Marie-Tooth disease) * Pregnancy or breastfeeding * Implanted cardiac pacemaker, defibrillator, or other active electronic implant * Active malignancy at or near the treatment site * Current use of photosensitising medications (e.g., tetracyclines, amiodarone, psoralens) * Corticosteroid injection into the carpal tunnel within the preceding 3 months * Rheumatoid arthritis or other inflammatory joint disease affecting the wrist * Open wounds, acute skin infection, or tattooed skin at the treatment site * Inability to attend 3 sessions per week for 4 weeks * Severe CTS confirmed by NCS (complete sensory or motor axon loss)

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Lahore Hospital

    Lahore, Punjab Province, 54000, Pakistan

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