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Light therapy may soothe wrist pain without surgery

NCT ID NCT07788248

Symptom relief Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether low-level laser therapy can reduce symptoms and improve hand function in people with mild-to-moderate carpal tunnel syndrome, a common condition where the median nerve in the wrist is compressed. Participants will be randomly assigned to receive either active laser therapy, a sham (inactive) laser, or paraffin bath therapy, all alongside standard care like wrist splinting and exercises. The study measures changes in symptom severity, nerve function, and hand strength before treatment, right after the 3-week session, and at a 3-month follow-up.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-level laser therapy (LLLT) using a device that delivers 670 nm wavelength light to the wrist, compared with paraffin bath therapy and a sham (inactive) laser.
What this could lead to
If effective, low-level laser therapy could become a non-invasive, drug-free option to reduce pain and numbness and improve hand function in people with mild-to-moderate carpal tunnel syndrome.
What could go wrong
This is a relatively small trial, and results may not apply to severe cases. The therapy might not outperform the sham or paraffin bath, and benefits may not last beyond three months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 105 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of mild-to-moderate carpal tunnel syndrome (unilateral or bilateral), confirmed by paresthesia and pain in the median nerve distribution, positive Tinel's and Phalen's signs on physical examination, and electrophysiologically confirmed mild-to-moderate CTS * Age 18 years or older * No cognitive impairment * Provision of informed consent to participate in the study Exclusion Criteria: * Cognitive impairment * Severe-stage CTS with surgery planned * Neurological disease affecting the extremity with CTS * Active local infection at the treatment site (e.g., cellulitis, erysipelas, thrombophlebitis) contraindicating physical therapy * Cardiac pacemaker (contraindication to physical therapy and electrodiagnostic studies) * Prior wrist fracture or laceration at the treatment site * Injection therapy for CTS within the past 3 months * Prior CTS surgery with recurrence * Active malignancy under treatment * Pregnancy

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital

    Bursa, Turkey (Türkiye)

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