Voice box transplant trial hopes to give speech back to patients
NCT ID NCT03269396
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether transplanting a donor voice box (larynx) can safely restore voice, swallowing, and breathing in people with severe larynx damage or who have had their larynx removed. Ten adults will receive the transplant and be followed for five years. The trial is currently on hold.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
larynx allograft (donor voice box)
What this could lead to
If successful, this could offer a way to restore natural voice, swallowing, and breathing for people who have lost larynx function due to injury or surgery.
What could go wrong
This is a very early, small study (10 people) that is currently suspended. The procedure carries major risks, including rejection of the transplant and the need for lifelong immune-suppressing drugs.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic in Arizona
Phoenix, Arizona, 85054, United States