Less invasive surgery for cervical cancer put to the test

NCT ID NCT06836869

Recruiting now Disease control Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a newer, less invasive laparoscopic hysterectomy (with special tumor-free techniques) to the standard open abdominal surgery for stage IB2 cervical cancer. About 524 women will be randomly assigned to one of the two surgeries. The main goal is to see if the laparoscopic approach is as effective at preventing cancer recurrence over 4.5 years, while also being safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Laparoscopic radical hysterectomy with modified tumor-free techniques
What this could lead to: If successful, this could offer a less invasive surgical option for stage IB2 cervical cancer with similar effectiveness and fewer complications.
What could go wrong: This is a non-inferiority trial, so the laparoscopic approach may prove no better than the standard. Results may not apply to other cancer stages or types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER STAGE IB2

Contacts and locations

Locations

Affiliated Hospital of North Sichuan Medical College
RECRUITING

Nanchong, Sichuan, 637000, China
Affiliated Hospital of Shanxi University of Traditional Chinese Medicine
RECRUITING

Xianyang, Shanxi, 712000, China
Cangzhou Central Hospital
RECRUITING

Cangzhou, Hebei, 061000, China
Hunan Provincial Maternal and Child Health Care Hospital
RECRUITING

Changsha, Hunan, 410000, China
Obstetrics & Gynecology Hospital of Fudan University
RECRUITING

Shanghai, China
Peking Union Medical College Hospital
RECRUITING

Beijing, 100079, China
Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School
RECRUITING

Shanghai, Shanghai Municipality, 200001, China
Sichuan Cancer Hospital and Institute
RECRUITING

Chengdu, China
Southwest Hospital
RECRUITING

Chongqing, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, 510120, China
The First Hospital of Lanzhou University
NOT_YET_RECRUITING

Lanzhou, Gansu, 730000, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050011, China
The Fourth Military Medical University, Xijing Hospital
RECRUITING

Xi’an, Shanxi, 710032, China
The Second Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130041, China
Tianjin Central Hospital of Gynecology Obstetrics
RECRUITING

Tianjin, China
Tongji Medical College
RECRUITING

Wuhan, China
Zhejiang cancer hospital
RECRUITING

Hangzhou, Zhejiang, 310022, China

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