Less invasive surgery for cervical cancer put to the test

NCT ID NCT06836869

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a newer, less invasive laparoscopic hysterectomy (with special tumor-free techniques) to the standard open abdominal surgery for stage IB2 cervical cancer. About 524 women will be randomly assigned to one of the two surgeries. The main goal is to see if the laparoscopic approach is as effective at preventing cancer recurrence over 4.5 years, while also being safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Laparoscopic radical hysterectomy with modified tumor-free techniques

What this could lead to

If successful, this could offer a less invasive surgical option for stage IB2 cervical cancer with similar effectiveness and fewer complications.

What could go wrong

This is a non-inferiority trial, so the laparoscopic approach may prove no better than the standard. Results may not apply to other cancer stages or types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of North Sichuan Medical College

    RECRUITING

    Nanchong, Sichuan, 637000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Affiliated Hospital of Shanxi University of Traditional Chinese Medicine

    RECRUITING

    Xianyang, Shanxi, 712000, China

    Contact Email: •••••@•••••

  • Cangzhou Central Hospital

    RECRUITING

    Cangzhou, Hebei, 061000, China

    Contact Email: •••••@•••••

  • Hunan Provincial Maternal and Child Health Care Hospital

    RECRUITING

    Changsha, Hunan, 410000, China

    Contact Email: •••••@•••••

  • Obstetrics & Gynecology Hospital of Fudan University

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, 100079, China

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School

    RECRUITING

    Shanghai, Shanghai Municipality, 200001, China

    Contact Email: •••••@•••••

  • Sichuan Cancer Hospital and Institute

    RECRUITING

    Chengdu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southwest Hospital

    RECRUITING

    Chongqing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510120, China

    Contact Email: •••••@•••••

  • The First Hospital of Lanzhou University

    NOT_YET_RECRUITING

    Lanzhou, Gansu, 730000, China

    Contact Email: •••••@•••••

  • The Fourth Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, 050011, China

    Contact Email: •••••@•••••

  • The Fourth Military Medical University, Xijing Hospital

    RECRUITING

    Xi’an, Shanxi, 710032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130041, China

    Contact Email: •••••@•••••

  • Tianjin Central Hospital of Gynecology Obstetrics

    RECRUITING

    Tianjin, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Medical College

    RECRUITING

    Wuhan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang cancer hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••