Morphine in spinal epidural may reduce breakthrough labor pain

NCT ID NCT06572241

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a small dose of morphine to the spinal part of a combined spinal-epidural injection can reduce sudden pain during labor. Researchers will compare morphine to a placebo in 182 first-time mothers. The goal is to see if morphine helps prevent breakthrough pain and improves overall comfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

morphine

What this could lead to

If it works, this could provide better pain relief during labor with fewer episodes of breakthrough pain.

What could go wrong

This is a small, early-stage trial. The addition of morphine may not significantly reduce pain and could have side effects like itching or nausea.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Labor Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G1X5, Canada

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact