Scientists pinpoint ideal painkiller dose for easier labor

NCT ID NCT06146842

Recruiting now Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial tests different doses of bupivacaine, a common painkiller, given through an epidural after a lidocaine test dose to women in labor. The goal is to find the dose that provides effective pain relief for 90% of participants. The study includes women with a single, full-term pregnancy who request an epidural for labor pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bupivacaine Hydrochloride
What this could lead to: If successful, this could identify the optimal bupivacaine dose for faster, more reliable pain relief during labor, improving comfort for mothers.
What could go wrong: This is a small, early-phase dose-finding study, not a large effectiveness trial. Results may not apply to all labor situations or techniques.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Labor Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LABOR PAIN

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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