New combo therapy targets deadly brain cancer recurrence
NCT ID NCT06336291
First seen Apr 25, 2026 · Last updated Jun 15, 2026 · Updated 14 times
Summary
This study tests a combination of two drugs, L19TNF and lomustine, in about 90 adults whose glioblastoma has come back or worsened. The goal is to find the safest and most effective dose, and to see if it helps people live longer. Participants must have a confirmed diagnosis and be well enough to undergo treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Beth Israel Deaconess Medical Center (BIDMC)
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute (DFCI)
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital (MGH)
Boston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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The University of Texas, MD Anderson Cancer Center
Houston, Texas, 77030, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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University of Virginia (UVA)
Charlottesville, Virginia, 22903, United States
Conditions
Explore the condition pages connected to this study.