Amino acid hope: could L-Serine boost brain health in depressed seniors?

NCT ID NCT07497347

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking L-serine, a natural amino acid supplement, can improve memory, thinking, and mood in older adults (ages 65-85) with late-life depression. Half of the 84 participants will receive L-serine daily for 48 weeks, while the other half receives a placebo. Researchers will track changes in depression, cognitive function, and brain activity to see if the supplement offers any benefit.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Centro San Giovanni di Dio Fatebenefratelli

    RECRUITING

    Brescia, 25125, Italy

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