CAR-T therapy takes on scleroderma: a new hope for patients

NCT ID NCT06400303

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 24 times

Summary

This early-stage study tests a new treatment called KYV-101 for people with systemic sclerosis, a rare autoimmune disease that causes skin and organ hardening. The therapy uses a patient's own modified immune cells to target and destroy faulty B-cells. The main goals are to check safety and see if it can improve disease symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Northwell Health

    Great Neck, New York, 11021, United States

  • Stanford University Medical Center

    Palo Alto, California, 94305, United States

Conditions

Explore the condition pages connected to this study.