Experimental CAR t therapy takes aim at lupus kidney disease
NCT ID NCT06342960
First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 30 times
Summary
This early-phase study tests a new treatment called KYV-101 for people with lupus nephritis that hasn't responded to standard therapies. The treatment uses a patient's own immune cells, modified to target and destroy harmful B cells that drive the disease. The main goals are to check safety and see how the therapy behaves in the body. Only 2 adults with active lupus kidney disease are being enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Charite- Universitätsklinikum Berlin
Berlin, Germany
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Fraunhofer-Institut für Translationale Medizin und Pharmakologie ITMP
Frankfurt, Germany
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Universitätsklinikum Carl Gustav Carus Dresden
Dresden, Germany
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Universitätsklinikum Düsseldorf
Düsseldorf, Germany
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Universitätsklinikum Erlangen
Erlangen, Germany
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Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany
Conditions
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