CAR T-Cell therapy shows promise for tough blood cancers in japanese patients

NCT ID NCT06253663

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 20 times

Summary

This study tests a treatment called KTE-X19, a type of CAR T-cell therapy, in 25 Japanese adults whose mantle cell lymphoma or B-cell acute lymphoblastic leukemia has come back or not responded to other treatments. The goal is to see how well it shrinks or eliminates the cancer and to check for side effects. Participants receive their own immune cells that have been modified to attack the cancer.

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Contacts and locations

Locations

  • Chiba University Hospital

    Chiba, 260-8677, Japan

  • Hokkaido University Hospital

    Hokkaido, 060-8648,, Japan

  • Juntendo University Hospital

    Tokyo, 113-8431, Japan

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • Kyushu University Hospital

    Fukuoka, 812-8582, Japan

  • National Cancer Center Hospital

    Tokyo, 104-0045, Japan

  • Okayama University Hospital

    Okayama, 700-8558, Japan

  • Tohoku University Hospital

    Miyagi, 980-8574, Japan

  • Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital

    Tokyo, 113-8677, Japan

Conditions

Explore the condition pages connected to this study.