Experimental CAR-T therapy takes on relapsed blood cancers

NCT ID NCT07234045

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study is testing a new treatment called CT1195E CAR-T cells in 30 adults with B-cell blood cancers that have come back or not responded to standard treatments. The therapy involves modifying a patient's own immune cells to better recognize and attack cancer cells. The main goals are to check the safety and find the right dose, while also looking at how well it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CT1195E CAR-T cells (a type of immune cell therapy)

What this could lead to

If successful, this could point toward a new treatment option for patients with hard-to-treat B-cell blood cancers that have not responded to standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 30 participants, so it is primarily testing safety and dosing. The therapy may not work well or could cause serious side effects, and it is far from being widely available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia B-cell adult acute lymphocytic leukemia B-cell neoplasm B-cell non-Hodgkin lymphoma Burkitt lymphoma follicular lymphoma mantle cell lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Institute of Hematology and Blood Diseases Hospital

    Tianjin, Tianjin Municipality, 301617, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact