Rare Virus-Linked cancer study tests multiple drug combos

NCT ID NCT00092222

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study looks at a rare, often fatal disease called KSHV-associated multicentric Castleman's disease (MCD). It aims to understand how the disease works and test several experimental treatments, including high-dose zidovudine, valganciclovir, bortezomib, rituximab, and interferon. About 75 adults will participate, undergoing extra blood draws and tumor biopsies. The study may not directly help participants but could improve future treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.