New study targets rare Virus-Driven inflammatory syndrome

NCT ID NCT01419561

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 6 times

Summary

This study looks at a newly recognized disease called KSHV Inflammatory Cytokine Syndrome (KICS), caused by a virus that can also lead to certain cancers. Researchers aim to learn more about the disease and test experimental treatments, including antiviral and chemotherapy drugs, in people with KICS. The study involves regular check-ups, blood tests, and imaging to track the disease and response to treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Zidovudine, liposomal doxorubicin, and valganciclovir (antiviral and chemotherapy drugs)
What this could lead to
If successful, this study could lead to better understanding and treatment options for KICS, a severe inflammatory condition caused by a virus.
What could go wrong
This is an early-phase study with a small number of participants, so results may not apply to everyone. The treatments can have side effects, and it's unclear if they will effectively control the disease long-term.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.