New study tests if extra nerve block can cut opioid use after knee replacement
NCT ID NCT07526831
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of nerve blocks for pain relief after total knee replacement. One group gets a standard adductor canal block, while the other gets that block plus an IPACK block. Researchers will measure pain scores and how much morphine patients need in the first 24 hours after surgery. The goal is to see if the combined approach offers better pain control with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nerve block procedure (adductor canal block with or without IPACK block)
What this could lead to
If successful, this could show that adding an IPACK block provides better pain relief and reduces the need for strong painkillers after knee surgery.
What could go wrong
This is a small, early-stage study with only 60 participants. The results may not apply to all patients, and the added block may not provide significant extra benefit.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sibel Pehlivan
RECRUITINGKayseri, Talas, 38090, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sibel Seckin Pehlivan
RECRUITINGKayseri, 38039, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••