New study tests if extra nerve block can cut opioid use after knee replacement

NCT ID NCT07526831

Recruiting now Symptom relief Sponsor: TC Erciyes University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of nerve blocks for pain relief after total knee replacement. One group gets a standard adductor canal block, while the other gets that block plus an IPACK block. Researchers will measure pain scores and how much morphine patients need in the first 24 hours after surgery. The goal is to see if the combined approach offers better pain control with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nerve block procedure (adductor canal block with or without IPACK block)
What this could lead to: If successful, this could show that adding an IPACK block provides better pain relief and reduces the need for strong painkillers after knee surgery.
What could go wrong: This is a small, early-stage study with only 60 participants. The results may not apply to all patients, and the added block may not provide significant extra benefit.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE ARTHROPLASTY, TOTAL

Contacts and locations

Locations

Sibel Pehlivan
RECRUITING

Kayseri, Talas, 38090, Turkey (Türkiye)
Sibel Seckin Pehlivan
RECRUITING

Kayseri, 38039, Turkey (Türkiye)

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