Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can zapping muscles while you flex them ease knee arthritis?

NCT ID NCT06277570

Symptom relief Sponsor: Gulhane School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 25, 2026 · Last updated Sep 25, 2026

Summary

Researchers are testing whether neuromuscular electrical stimulation, delivered while participants actively contract their muscles, can improve physical function, muscle strength, joint position sense, and quality of life in people with knee osteoarthritis. The trial enrolls adults aged 40 to 65 with moderate knee osteoarthritis. Participants receive either conventional physiotherapy alone or conventional physiotherapy plus the superimposed stimulation technique, and researchers measure outcomes like knee strength and joint awareness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
superimposed neuromuscular electrical stimulation, a technique that adds electrical pulses to voluntary muscle contractions
What this could lead to
If it works, this could offer a non-invasive way to boost muscle strength and joint control for people with knee osteoarthritis, possibly alongside standard physiotherapy.
What could go wrong
The trial is small and early, so any benefits may be modest or not hold up in larger studies. Electrical stimulation can cause skin irritation or discomfort, and results may not apply to everyone with knee osteoarthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

63 people

The number who actually took part.

Started

Oct 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Having grade 2-3 knee osteoarthritis according to Kellgren and Lawrence Classification, * Being between the ages of 40-65, , * Being literate * Volunteer Exclusion Criteria: * Having Grade 2 or higher osteoarthritis in the hip, ankle, or foot joint Presence of a history of knee-related surgery (arthroplasty, meniscectomy, etc.) * Having a deformity in the waist, leg, hip, knee, or ankle * Having any inflammatory rheumatic, neurological, vestibular, cardiopulmonary disease * Having active knee joint synovitis * BMI\>40 * Having a condition that is contraindicate for electrotherapy (malignancy, pacemaker, epilepsy, deep vein thrombosis, loss of protective sensation, etc.) * Having received physiotherapy in the last 3 months * Being diagnosed with a psychiatric disease * Having a cooperation problem that makes it difficult to comply with evaluation and treatment

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Knee osteoarthritis are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Faculty of Physiotherapy and Rehabilitation, University of Health Sciences

    Ankara, Etlik, 06018, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.