Can we predict who gets knee pain relief from a common gel?
NCT ID NCT06574191
First seen Jun 25, 2026 · Last updated Jun 25, 2026
Summary
This study is testing whether patient traits and clinic visit factors can predict how well topical diclofenac gel relieves knee osteoarthritis pain. 220 adults aged 50+ with confirmed knee OA will use the gel for 8 weeks and complete questionnaires and blood draws. The goal is to personalize treatment by identifying who responds best.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for KNEE OSTEOARTHRITIS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
University of California Davis Health
RECRUITINGSacramento, California, 95817, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Topical diclofenac gel 1%
What this could lead to
If successful, this could help doctors predict which knee osteoarthritis patients will benefit most from topical diclofenac, leading to more personalized pain management.
What could go wrong
This is an observational study, not a treatment trial. It aims to find predictors, not prove the gel works. Results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.