Shot in the dark: can a double injection beat knee arthritis pain?

NCT ID NCT06685120

Recruiting now Symptom relief Sponsor: Istituto Ortopedico Rizzoli Source: ClinicalTrials.gov ↗

First seen Dec 04, 2025 · Last updated Apr 13, 2026 · Updated 16 times

Summary

This study aims to see if a combination injection of platelet-rich plasma (PRP) and hyaluronic acid works better than either injection alone for knee osteoarthritis. It will involve 288 adults with knee pain who haven't gotten enough relief from standard treatments. Participants will receive one type of injection and be followed for two years to measure changes in pain, stiffness, and daily function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

IRCCS Istituto Ortopedico Rizzoli
NOT_YET_RECRUITING

Bologna, 40136, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Ortopedico Rizzoli
RECRUITING

Bologna, 40136, Italy

Contact Email: •••••@•••••

Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

OSTEO ARTHRITIS KNEE