New drug trial targets Hard-to-Treat cancer mutations
NCT ID NCT04913285
Summary
This early-stage study is testing a new oral drug called KIN-2787 in adults with advanced solid tumors that have specific BRAF or NRAS gene mutations, including lung cancer and melanoma. The main goals are to find a safe dose, see how the body processes the drug, and get an early look at whether it can shrink tumors, both alone and when combined with another cancer drug. It is enrolling up to 400 participants who have run out of standard treatment options.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHM-CHU La Timone
Marseille, France
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APHP - Hôpital St Louis
Paris, France
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Arance
Barcelona, Spain, Spain
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Atlantic Health
Morristown, New Jersey, 07960, United States
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Austin Health
Heidelberg, Victoria, 3084, Australia
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Beijing University Cancer Hospital
Beijing, 100142, China
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Berrocal
Valencia, Spain, Spain
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CHU Nantes-Hotel Dieu
Nantes, France
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CHU de Lille
Lille, France
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CHU de Nice - Hôpital Archet 2
Nice, France
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CHU de Poitiers
Poitiers, France
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Calvary Mater Hospital Newcastle
Waratah, New South Wales, 2298, Australia
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Centre Francois Baclesse
Caen, France
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Centre Leon Berard
Lyon, France
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Gustave Roussy
Villejuif, 94805, France
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H. Regional de Málaga
Málaga, Spain, Spain
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H. Virgen Macarena
Seville, Spain, Spain
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Harbin Medical University Cancer Hospital
Haerbin, Heilongjiang, 150081, China
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Hospices Civiles de Lyon - Hôpital Lyon Sud
Pierre-Bénite, France
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Hospital General Gregorio Marañón
Madrid, 29009, Spain
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Hospital Quiron Dexeus
Barcelona, Spain
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Hospital Universitario Insular de Gran Canaria
Las Palmas de Gran Canaria, Spain
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INCLIVA (Hospital Clinico de Valencia)
Valencia, Spain
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Institut Bergonie
Bordeaux, France
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Istituto Nazionale dei Tumori Fondazione G. Pascale
Naples, 80131, Italy
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Linear Clinical Research
Perth, Western Australia, 6009, Australia
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Linyi Cancer Hospital
Linyi, Shandong, 276001, China
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MD Anderson
Houston, Texas, 77030, United States
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Mayo Clinic - Florida
Jacksonville, Florida, 32224, United States
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Mayo Clinic - Rochester
Rochester, Minnesota, 55905, United States
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Melanoma Institute Australia
Wollstonecraft, New South Wales, 2065, Australia
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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NEXT Quirónsalud Madrid
Madrid, Spain, Spain
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NYU Langone
New York, New York, 10016, United States
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National Taiwan University Hospital
Taipei, Taiwan
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Oncopole Claudius Regaud
Toulouse, 31059, France
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
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START Madrid
Madrid, 28050, Spain
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Sarah Cannon Research Institute - Florida Cancer Specialists
Orlando, Florida, 32827, United States
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Sarah Cannon Research Institute Denver
Denver, Colorado, 80218-1238, United States
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Sarah Cannon Research Institute-Tennessee Oncology
Nashville, Tennessee, 37203, United States
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Stanford Cancer Center
Stanford, California, 94305, United States
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Tasman Health Care
Southport, Queensland, 4215, Australia
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The Angeles Clinic
Los Angeles, California, 90025-6602, United States
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The Shanghai Pulmonary Hospital
Shanghai, 200433, China
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UCLA
Los Angeles, California, 90095, United States
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University of California San Diego, Moores Cancer Center
San Diego, California, 92093, United States
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University of California San Francisco
San Francisco, California, 94143-2205, United States
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Virginia Cancer Specialists
Fairfax, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.