Zapping kidney nerves to tame stubborn high blood pressure

NCT ID NCT02439775

Summary

This study tested if a medical procedure could safely lower blood pressure in people whose high blood pressure wasn't controlled by up to three standard medications. Doctors used a special device to disrupt tiny nerves near the kidneys, which are thought to play a role in regulating blood pressure. The goal was to see if this approach provided better blood pressure control compared to a fake procedure, while monitoring for safety issues.

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Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • AnMed Health

    Anderson, South Carolina, 29621, United States

  • Aurora St. Luke's Medical Center

    Milwaukee, Wisconsin, 53215, United States

  • Baptist Medical Center Jacksonville

    Jacksonville, Florida, 32207, United States

  • Barnes-Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Baylor Heart & Vascular Hospital

    Dallas, Texas, 75226, United States

  • Cardiff and Vale University Health Board - University Hospital of Wales

    Cardiff, United Kingdom

  • Cardiology Associates Research LLC

    Tupelo, Mississippi, 38801, United States

  • Centennial Medical Center

    Nashville, Tennessee, 37203, United States

  • Charleston Area Medical Center

    Charleston, West Virginia, 25304, United States

  • Clinique Pasteur

    Toulouse, France

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Galway University Hospital

    Galway, Ireland

  • Hamilton Heath

    Hamilton, Ontario, Canada

  • Hattiesburg Clinic

    Hattiesburg, Mississippi, 39401, United States

  • Heart Center Research, LLC

    Huntsville, Alabama, 35801, United States

  • Herzzentrum Leipzig, Universitätsklinik

    Leipzig, 04289, Germany

  • Higashi Takarazuka Satoh Hospital

    Takarazuka, Hyōgo, Japan

  • Hippokration General Hospital of Athens

    Athens, 11527, Greece

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Imperial College Healthcare NHS Trust

    London, W12 0HS, United Kingdom

  • Iowa Heart Center

    West Des Moines, Iowa, 50266, United States

  • Jichi Medical University Hospital

    Shimotsuke, Tochigi, 329-0498, Japan

  • Klinikum Wels-Grieskirchen

    Wels, 4600, Austria

  • Memorial Hospital Jacksonville

    Jacksonville, Florida, 32216, United States

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407, United States

  • Mitsui Memorial Hospital

    Chiyoda City, Tokyo, 101-8643, Japan

  • Mount Sinai Medical Center

    New York, New York, 10029, United States

  • North Shore University Hospital

    Manhasset, New York, 11030, United States

  • Oregon Health & Science University Hospital

    Portland, Oregon, 97239, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • PinnacleHealth Cardiovascular Institute

    Harrisburg, Pennsylvania, 17011, United States

  • Providence Hospital

    Southfield, Michigan, 48075, United States

  • Royal Bournemouth Hospital

    Bournemouth, United Kingdom

  • Royal Devon & Exeter NHS Foundation Trust

    Exeter, EX2 5DW, United Kingdom

  • Royal Perth

    Perth, Australia

  • Saint Barnabas Medical Center

    Livingston, New Jersey, 07039, United States

  • Saiseikai Nakatsu Hospital

    Osaka, Japan

  • Sana Kliniken Lübeck

    Lübeck, 23560, Germany

  • Shonan Kamakura General Hospital

    Kamakura, Okamoto, Japan

  • St Joseph Mercy Oakland

    Pontiac, Michigan, 48341, United States

  • St. George Hospital

    Kogarah, Australia

  • St. Michael's Hospital

    Toronto, Ontario, Canada

  • Stanford Hospital and Clinics

    Stanford, California, 94305, United States

  • Tallahassee Research Institute

    Tallahassee, Florida, 32308, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • University General Hospital of Thessaloniki (AHEPA)

    Thessaloniki, 54621, Greece

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Kentucky

    Lexington, Kentucky, 40536, United States

  • Universitäts-Herzzentrum Freiburg - Bad Krozingen GmbH

    Bad Krozingen, 79189, Germany

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum des Saarlandes

    Homburg, 66421, Germany

  • Washington DC VA Medical Center

    Washington D.C., District of Columbia, 20422, United States

  • Weill Cornell Medical College/The New York Presbyterian Hospital

    New York, New York, 10021, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.