Major trial halted: did a common drug fail to protect kidneys?

NCT ID NCT05056727

Terminated Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large international study aimed to see if a drug called sodium zirconium cyclosilicate (SZC), which lowers blood potassium, could help slow the worsening of chronic kidney disease (CKD). It involved over 1,100 adults with CKD who either had high potassium or were at risk for it. The study tested if taking SZC alongside standard blood pressure medications could better protect kidney function over two years compared to a placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Surprise, Arizona, 85374, United States
Research Site

Tucson, Arizona, 85741, United States
Research Site

Canyon Country, California, 91351, United States
Research Site

Chula Vista, California, 91910, United States
Research Site

Northridge, California, 91324, United States
Research Site

San Dimas, California, 91773, United States
Research Site

South Gate, California, 90280, United States
Research Site

Tarzana, California, 91356, United States
Research Site

Denver, Colorado, 80230, United States
Research Site

Boynton Beach, Florida, 33435, United States
Research Site

Hialeah, Florida, 33012, United States
Research Site

Lauderdale Lakes, Florida, 33313, United States
Research Site

Ocoee, Florida, 34761, United States
Research Site

Temple Terrace, Florida, 33637, United States
Research Site

Nampa, Idaho, 83687, United States
Research Site

Chicago, Illinois, 60643, United States
Research Site

Oak Brook, Illinois, 60523, United States
Research Site

Fort Wayne, Indiana, 46804, United States
Research Site

Louisville, Kentucky, 40205, United States
Research Site

Boston, Massachusetts, 02114, United States
Research Site

Boston, Massachusetts, 02115, United States
Research Site

Flint, Michigan, 48532, United States
Research Site

Saint Clair Shores, Michigan, 48081, United States
Research Site

Columbia, Missouri, 65201, United States
Research Site

Kansas City, Missouri, 64111, United States
Research Site

Albuquerque, New Mexico, 87109, United States
Research Site

Albany, New York, 12205, United States
Research Site

Great Neck, New York, 11021, United States
Research Site

Winston-Salem, North Carolina, 27103, United States
Research Site

Cincinnati, Ohio, 45267, United States
Research Site

Bethlehem, Pennsylvania, 18017, United States
Research Site

Chester, Pennsylvania, 19013, United States
Research Site

Columbia, South Carolina, 29203, United States
Research Site

Orangeburg, South Carolina, 29118, United States
Research Site

Chattanooga, Tennessee, 37404, United States
Research Site

Arlington, Texas, 76015, United States
Research Site

Fort Worth, Texas, 76164, United States
Research Site

Houston, Texas, 77004, United States
Research Site

Houston, Texas, 77054, United States
Research Site

Houston, Texas, 77099, United States
Research Site

San Antonio, Texas, 78212, United States
Research Site

Newport News, Virginia, 23606, United States
Research Site

Buenos Aires, ARG 1425, Argentina
Research Site

Buenos Aires, C1429BWN, Argentina
Research Site

CABA, C1440AAD, Argentina
Research Site

La Plata, 1900, Argentina
Research Site

Mar del Plata, 7600, Argentina
Research Site

Mar del Plata, B7600, Argentina
Research Site

Rosario, 2000, Argentina
Research Site

San Vicente, 5006, Argentina
Research Site

Sarandí, B1872EEC, Argentina
Research Site

Curitiba, 80440-020, Brazil
Research Site

Fortaleza, 60115282, Brazil
Research Site

Joinville, 89227-680, Brazil
Research Site

Maringá, 87060-040, Brazil
Research Site

Porto Alegre, 90020-090, Brazil
Research Site

Porto Alegre, 90160-093, Brazil
Research Site

São Paulo, 04039-000, Brazil
Research Site

São Paulo, 05403-9000, Brazil
Research Site

Blagoevgrad, 2700, Bulgaria
Research Site

Botevgrad, 2140, Bulgaria
Research Site

Dupnitsa, 2600, Bulgaria
Research Site

Gorna Oryahovitsa, 5100, Bulgaria
Research Site

Gotse Delchev, 2900, Bulgaria
Research Site

Kozloduy, 3320, Bulgaria
Research Site

Lom, 3600, Bulgaria
Research Site

Pleven, 5800, Bulgaria
Research Site

Plovdiv, 4000, Bulgaria
Research Site

Plovdiv, 4001, Bulgaria
Research Site

Plovdiv, 4004, Bulgaria
Research Site

Samokov, 2000, Bulgaria
Research Site

Sandanski, 2800, Bulgaria
Research Site

Silistra, 7500, Bulgaria
Research Site

Sliven, 8800, Bulgaria
Research Site

Smolyan, 3700, Bulgaria
Research Site

Stara Zagora, 6000, Bulgaria
Research Site

Yambol, 8600, Bulgaria
Research Site

Saint John, New Brunswick, E2L 4L2, Canada
Research Site

Oshawa, Ontario, L1G 2B9, Canada
Research Site

Montreal, Quebec, H1T 2M4, Canada
Research Site

Montreal, Quebec, H4J 1C5, Canada
Research Site

Baotou, 014010, China
Research Site

Beijing, 100029, China
Research Site

Beijing, 100034, China
Research Site

Beijing, 100044, China
Research Site

Beijing, 100191, China
Research Site

Beijing, 102206, China
Research Site

Beijing, 102218, China
Research Site

Changchun, 130041, China
Research Site

Changsha, 410013, China
Research Site

Chengdu, 610041, China
Research Site

Chengdu, 610072, China
Research Site

Chongqing, 400010, China
Research Site

Guangzhou, 510000, China
Research Site

Guangzhou, 510062, China
Research Site

Guangzhou, 510180, China
Research Site

Guangzhou, 510630, China
Research Site

Guiyang, 550002, China
Research Site

Hangzhou, 310014, China
Research Site

Hefei, 230601, China
Research Site

Hengyang, 421001, China
Research Site

Huizhou, 516001, China
Research Site

Lanzhou, 730030, China
Research Site

Nanchang, 330006, China
Research Site

Nanjing, 210009, China
Research Site

Nanjing, 210011, China
Research Site

Nanjing, 210029, China
Research Site

Ningbo, 315010, China
Research Site

Sanya, 572000, China
Research Site

Shanghai, 200025, China
Research Site

Shanghai, 200040, China
Research Site

Shanghai, 201199, China
Research Site

Shanghai, 201210, China
Research Site

Shantou, 515041, China
Research Site

Shengyang, 110004, China
Research Site

Shenyang, 110001, China
Research Site

Shenzhen, 518036, China
Research Site

Taiyuan, 030012, China
Research Site

Ürümqi, 830054, China
Research Site

Wuhan, 430010, China
Research Site

Wuhan, 430060, China
Research Site

Wuxi, 214023, China
Research Site

Xi'an, 710061, China
Research Site

Xuzhou, 221000, China
Research Site

Yantai, 264000, China
Research Site

Yinchuan, 750004, China
Research Site

Zhengzhou, 450052, China
Research Site

Zhuzhou, 412007, China
Research Site

Coimbatore, 641018, India
Research Site

Kolkata, 700020, India
Research Site

Madurai, 625107, India
Research Site

New Delhi, 110029, India
Research Site

Bari, 70124, Italy
Research Site

Bassano del Grappa, 36061, Italy
Research Site

Bologna, 40138, Italy
Research Site

Brescia, 25123, Italy
Research Site

Messina, 98125, Italy
Research Site

Pavia, 27100, Italy
Research Site

Roma, 00161, Italy
Research Site

Roma, 00168, Italy
Research Site

Rozzano, 20089, Italy
Research Site

San Giovanni Rotondo, 71013, Italy
Research Site

Verona, 37126, Italy
Research Site

Amagasaki-shi, 660-8550, Japan
Research Site

Atsugi-shi, 243-0035, Japan
Research Site

Chiba, 260-8712, Japan
Research Site

Chuo-shi, 409-3898, Japan
Research Site

Chūōku, 103-0002, Japan
Research Site

Chūōku, 104-8560, Japan
Research Site

Fukuoka, 814-0180, Japan
Research Site

Kamakura-shi, 247-0056, Japan
Research Site

Kanoya-shi, 893-0015, Japan
Research Site

Kasugai-shi, 486-8510, Japan
Research Site

Kawachinagano-shi, 586-8521, Japan
Research Site

Kawasaki-shi, 211-8510, Japan
Research Site

Kitakyushu, 805-8508, Japan
Research Site

Kitakyushu-shi, 802-8555, Japan
Research Site

Koriyama-shi, 963-8052, Japan
Research Site

Koshigaya-shi, 343-8555, Japan
Research Site

Kumamoto, 861-8520, Japan
Research Site

Kure-shi, 737-0023, Japan
Research Site

Marugame-shi, 763-8502, Japan
Research Site

Matsumoto-shi, 390-8621, Japan
Research Site

Matsusaka-shi, 515-8557, Japan
Research Site

Matsuyama, 790-8524, Japan
Research Site

Nagoya, 457-8511, Japan
Research Site

Nagoya, 466-8650, Japan
Research Site

Naka, 311-0113, Japan
Research Site

Noda, 278-8501, Japan
Research Site

Osaka, 543-8922, Japan
Research Site

Osaka, 559-0012, Japan
Research Site

Ōita, 870-0033, Japan
Research Site

Ōmihachiman, 523-0082, Japan
Research Site

Sakaishi, 593-8304, Japan
Research Site

Takarazuka-shi, 665-0873, Japan
Research Site

Toyota, 470-0396, Japan
Research Site

Toyota-Shi, 471-8513, Japan
Research Site

Tsu, 514-8507, Japan
Research Site

Tsuchiura-shi, 300-0028, Japan
Research Site

Urayasu-shi, 279-0021, Japan
Research Site

Yaizu-shi, 425-8505, Japan
Research Site

Yokohama, 227-8501, Japan
Research Site

Yokohama, 234-0054, Japan
Research Site

Yokohama, 236-0004, Japan
Research Site

Yonago-shi, 683-8605, Japan
Research Site

Alor Star, 5460, Malaysia
Research Site

Batu Caves, 68100, Malaysia
Research Site

Johor Bahru, 80100, Malaysia
Research Site

Kajang, 43000, Malaysia
Research Site

Kuala Lumpur, 50586, Malaysia
Research Site

Kuala Lumpur, 56000, Malaysia
Research Site

Kuala Lumpur, 59100, Malaysia
Research Site

Seri Manjung, 32040, Malaysia
Research Site

Cuauhtémoc, 06700, Mexico
Research Site

Culiacán, 80230, Mexico
Research Site

Guadalajara, 44670, Mexico
Research Site

Mazatlán, 82000, Mexico
Research Site

Mérida, 97070, Mexico
Research Site

Mérida, 97130, Mexico
Research Site

México, 03100, Mexico
Research Site

México, 06700, Mexico
Research Site

San Luis Potosí City, 78250, Mexico
Research Site

Veracruz, 91900, Mexico
Research Site

Davao City, PH-8000, Philippines
Research Site

Iloilo City, 5000, Philippines
Research Site

Krakow, 31-156, Poland
Research Site

Lodz, 92-213, Poland
Research Site

Poznan, 61-485, Poland
Research Site

Rzeszów, 35-055, Poland
Research Site

Tczew, 83-110, Poland
Research Site

Ponce, 00717, Puerto Rico
Research Site

Aramil, 624002, Russia
Research Site

Moscow, 123182, Russia
Research Site

Perm, 614000, Russia
Research Site

Rostov-on-Don, 344022, Russia
Research Site

Saint Petersburg, 191167, Russia
Research Site

Almería, 4009, Spain
Research Site

Barcelona, 08035, Spain
Research Site

Barcelona, 08036, Spain
Research Site

Barcelona, 8003, Spain
Research Site

Getafe, 28905, Spain
Research Site

L'Hospitalet de Llobregat, 08907, Spain
Research Site

Lugo, 27004, Spain
Research Site

Madrid, 28040, Spain
Research Site

Santa Cruz de Tenerife, 38010, Spain
Research Site

Seville, 41009, Spain
Research Site

Valencia, 46010, Spain
Research Site

Valencia, 46014, Spain
Research Site

Hualien City, 97002, Taiwan
Research Site

Kaohsiung City, 81362, Taiwan
Research Site

Kaohsiung City, 82445, Taiwan
Research Site

Kaohsiung City, 833, Taiwan
Research Site

Keelung, 20448, Taiwan
Research Site

New Taipei City, 220216, Taiwan
Research Site

New Taipei City, 23561, Taiwan
Research Site

Taichung, 40201, Taiwan
Research Site

Taichung, 40705, Taiwan
Research Site

Tainan, 70403, Taiwan
Research Site

Tainan, 710, Taiwan
Research Site

Taipei, 10002, Taiwan
Research Site

Taipei, 110, Taiwan
Research Site

Taipei, 114, Taiwan
Research Site

Taoyuan District, 333, Taiwan
Research Site

Bangkok, 10330, Thailand
Research Site

Bangkok, 10700, Thailand
Research Site

Chaingmai, 50200, Thailand
Research Site

Hat Yai, 90110, Thailand
Research Site

Ratchathewi, 10400, Thailand
Research Site

Adapazarı, 54100, Turkey (Türkiye)
Research Site

Ankara, 06230, Turkey (Türkiye)
Research Site

Ankara, 06340, Turkey (Türkiye)
Research Site

Ankara, 6230, Turkey (Türkiye)
Research Site

Antalya, 07059, Turkey (Türkiye)
Research Site

Gaziantep, 27310, Turkey (Türkiye)
Research Site

Istanbul, Turkey (Türkiye)
Research Site

Izmir, 35040, Turkey (Türkiye)
Research Site

Kahramanmaraş, 46100, Turkey (Türkiye)
Research Site

Kayseri, 38039, Turkey (Türkiye)
Research Site

Kocaeli, 41380, Turkey (Türkiye)
Research Site

Dnipropetrovsk, 49005, Ukraine
Research Site

Kharkiv, 61039, Ukraine
Research Site

Kyiv, 02125, Ukraine
Research Site

Kyiv, 03057, Ukraine
Research Site

Kyiv, 04050, Ukraine
Research Site

Kyiv, 04053, Ukraine
Research Site

Lutsk, 43005, Ukraine
Research Site

Vinnytsia, 21028, Ukraine
Research Site

Zaporizhzhia, 69001, Ukraine
Research Site

Zhytomyr, 10002, Ukraine
Research Site

Biên Hòa, 810000, Vietnam
Research Site

Da Nang, 55000, Vietnam
Research Site

Hanoi, 100000, Vietnam
Research Site

Ho Chi Minh City, 10000, Vietnam
Research Site

Ho Chi Minh City, 700000, Vietnam
Research Site

Ho Chi Minh City, 70000, Vietnam
Research Site

Huế, 530000, Vietnam

Conditions

Explore the condition pages connected to this study.

HYPERKALEMIA RENAL INSUFFICIENCY, CHRONIC